Mark London wrote:

Hi - I'm trying to figure out what this person's real surname would
have been, who was married in Massachusetts:
https://familysearch.org/pal:/MM9.1.1/N47P-TXR It clearly is written as Simon
Sampaner, but that surname doesn't show up in any record for that time period, in
Massachusetts. Does anyone have an idea what it might really have been? Thanks.

"Sampaner" is most probably a toponym, I guess,
like "Hamburger", "Londoner" or "Berliner".

Perhaps someone from:

Zempin, Mecklenburg-Vorpommern, Germany
Czempin, Poland
Zembin, Belarus

Or any of the many Câmpina / Cîmpina, Romania

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