49 India Street, Brooklyn (that's in Greenpoint)
father: Gerson Rothstein
mother: Brane Grau (or Grad)
234 E. 7th St.
father: Salomon Lewin
mother: Amalie Spauran (or Spawran)
Rabbi Rosenthal, Congregation Shearith B'nai Israel, 323 E. 4th St.
Witnesses: Salmon Spander and Charles Peysey
My guess is that "Salmon Spander" is related to Amalie. The surname Spander / Spauran is probably really the same name. Who knows what the actual spelling might be? That's why soundex searches are so valuable.
First off, spelling didn't count. Don't worry about vowel shifts in names.
To read more about Sadhora, Ukraine (modern name of town):
For some time before WW1 Sadhora was part of The Austrian Empire.
Regina's birthplace is probably Budzyń, Poland. It was part of Germany before WW1.
You can search The JewishGen Databases for old records of these towns at:
When searching the surname I suggest using a soundex (sounds like search) as spelling could vary widely in the records.
Good luck in your search,