There is no way to guess about her original name. I can tell you that my ggm Yenta was called Yetta after coming to The U.S. A hundred other ladies that called themselves Yetta may have had other names.
Your gm's Hebrew name may be on her tombstone.
Also, if she was born outside of The U.S. than her passenger manifest will list her under the name she used prior to arriving here.
Searching: RATOWSKY / CHAIMSON (Ariogala / Ragola, Lith.)
WALTZMAN / WALZMAN (Ustrzyki Dolne / Istryker, Pol.)
LEVY (Tyrawa Woloska, Pol.)
LEFFENFELD / LEFENFELD / FINK, KALTER (Daliowa/ Posada Jasliska, Pol.)
BOJDA / BERGER (Tarnobrzeg, Pol.)
SOKALSKY / SOLON / SOLAN / FINGER(MAN) (Grodek, Bialystok, Pol.)
BOBISH / APPEL (Odessa?)